Clobederm Cream:

 Clobederm Cream (Each 100g contains)

 Clobetasol PropionateUSP  0.05g (0.05% w/w)

Clobetasol Propionate is a synthetic corticosteroid designed for topical dermatological use. Chemically, Clobetasol Propionate is (11B, 16ß)21chloro9fluoro11hydroxy16methyl17(1oxopropoxy)pregna1, 4diene3, 20dione. Its molecular weight is 466.98

 Indications:

Clobederm Cream, a topical corticosteroid, is specifically used in short courses for the following conditions:

•  Psoriasis (excluding widespread plaque psoriasis)
•  Recalcitrant eczemas
•  Lichen planus
•  Discoid lupus erythematosus
•  Other skin conditions that are unresponsive to less potent steroids

 Dosage and Administration:

•  Apply a thin layer to the affected area once or twice daily until improvement is observed
•  Discontinue therapy once control is achieved
•  The treatment should not extend beyond four weeks without a physician’s review
•  For more resistant cases, occlusive dressings are recommended

 Contraindications:

Clobederm Cream should not be used for the following conditions:

•  Rosacea
•  Acne vulgaris
•  Perioral dermatitis
•  Primary cutaneous viral infections
•  Hypersensitivity to the preparation
•  Infections caused by fungi or bacteria in children under 1 year of age, including dermatitis and napkin eruptions

 Precautions & Warnings:

•  Avoid prolonged application to the face
•  Ensure the cream does not come into contact with the eyes, as it may lead to glaucoma.
•  Clobederm may mask infections
• Avoid prolonged use, particularly in children, to minimize the risk of adrenal issues.
•  Atrophic skin changes may occur after prolonged use
•  Use on eyelids with care
• Supervision should oversee the treatment of psoriasis patients.
•  Infected lesions may require systemic antibiotic therapy
•  In the case of infection spreading, discontinue Clobederm Cream

 Pregnancy & Lactation:

During pregnancy, avoid extensive use of topical steroids.

 Adverse Effects:

Prolonged use of large amounts or treatment of extensive

areas may cause:

•  Features of hyperpigmentation
•  Atrophy of the skin (thinning, striae)
•  Dilation of superficial blood vessels
•  Pigmentation changes
•  Hypertrichosis
•  Hypersensitivity
•  Exacerbations of symptoms
•  Treatment of psoriasis or its withdrawal may provoke the pustular form of the disease

 Instructions:

•  Keep out of reach of children
•  Protect from light and heat
•  Do not store above 30°C
•  Use as directed by a physician

 Presentations:

Clobederm Cream is available in 5gm and 10gm aluminum collapsible tubes